Journal article
Calibrated integrated backscatter and myocardial fibrosis in patients undergoing cardiac surgery
David L Prior, Jithendra B Somaratne, Alicia J Jenkins, Michael Yii, Andrew E Newcomb, Casper G Schalkwijk, Mary J Black, Darren J Kelly, Duncan J Campbell
OPEN HEART | BMJ PUBLISHING GROUP | Published : 2015
Abstract
OBJECTIVE: The reported association between calibrated integrated backscatter (cIB) and myocardial fibrosis is based on study of patients with dilated or hypertrophic cardiomyopathy and extensive (mean 15-34%) fibrosis. Its association with lesser degrees of fibrosis is unknown. We examined the relationship between cIB and myocardial fibrosis in patients with coronary artery disease. METHODS: Myocardial histology was examined in left ventricular epicardial biopsies from 40 patients (29 men and 11 women) undergoing coronary artery bypass graft surgery, who had preoperative echocardiography with cIB measurement. RESULTS: Total fibrosis (picrosirius red staining) varied from 0.7% to 4%, and in ..
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Grants
Awarded by National Health and Medical Research Council of Australia
Awarded by National Heart Foundation of Australia
Funding Acknowledgements
This study was funded by grants from the National Health and Medical Research Council of Australia (grant IDs 395508 and 566867) and from the National Heart Foundation of Australia (grant ID G08M 3833). St. Vincent's Institute of Medical Research is supported in part by the Victorian Government's Operational Infrastructure Support Program.